The colour ranges from a dark environment which led to black skin colour, to a light environment where light-coloured frogs were found. One day, Hogben and his team observed that the skin colour of the adult frogs was dependent on their growing environment. Hogben's earlier works revolved around pituitary hormones and frogs. The Hogben test uses female frogs, unlike the Galli-Mainini test which uses male frogs. The urine samples were injected into African clawed frogs. The Hogben test, named after the British zoologist Lancelot Hogben, was one of the most reliable and rapid pregnancy tests from the 1940s to the 1960s. In men, the hCG test can be used to screen for the presence of testicular cancer. The hCG test can also be done after a miscarriage to ensure that a molar pregnancy is not present. The hCG test can be used to screen for uterus cancer, or a molar pregnancy, which is when there is abnormal placental growth in the uterus. However, hCG can also be produced by germ cell tumours, which are tumours from eggs or sperms. In an individual, hCG should not be present unless they are pregnant. hCG blood tests can also screen for birth defects. Similarly, more hCG is released if the mother is carrying triplets, than if she is carrying twins. Less hCG is released in a single pregnancy. The amount of hCG can also reflect the pregnancy. Normally, the hCG level increases and peaks at the first 14 weeks of pregnancy, and no hCG is detected after the delivery of the baby. ![]() Therefore, they can be used as a screening for pregnancy, however the level of hCG can also provide information about the pregnancy. The pee-on-a-stick pregnancy test only detects the presence of hCG, and cannot measure the level of hCG in the blood. It takes around 6 days after the implantation of the fertilized egg, or just after the first menstrual period is missed, to detect hCG levels in the blood. Then, the placenta will begin to develop and release hCG into the mother's bloodstream, which can get passed into the urine. ![]() It takes approximately 9 days for the fertilized egg to move from the fallopian tubes to the uterus, where it implants itself into the walls of the uterus. Human chorionic gonadotrophin (hCG) is a hormone that is produced when a woman is pregnant, and this is because the placenta is responsible for its production. Widespread export and traffic in African clawed frogs used for these tests is believed to have been the primary cause of the intercontinental spread of chytridiomycosis. The Galli-Mainini test is another frog test developed based on similar principles. The most well known frog test, is the Hogben test, which is a pregnancy testing method prevalent throughout the 1940s to 1960s, by using the underlying principle of hormones and its subsequent biological response in both genders of certain frog species. Throughout history, there have been different frog tests with the aim of indicating the pregnancy status of women. The frog test or frog pregnancy test is one of the past prevalent pregnancy scanning methods. Before these accessible and convenient test kits were invented, scientists strived to discover a way in spotting pregnancy-related hormones by a natural, simple test, where animals were often included as clinical tools to facilitate the process. ![]() Nowadays, the advancement in medical technology has enabled women to accurately check their pregnancy status by using 'pee-on-a-stick' pregnancy test kits at home. ![]() Provided that immunological pregnancy tests were not yet developed before 1960s, women living a century ago relied on urine-based pregnancy tests using different animals, ranging from mice to frogs. The frog test is a pregnancy testing method relying on frogs to show the pregnancy status of women. ( May 2022) ( Learn how and when to remove this template message) Please help improve this article if you can. The specific problem is: still some unencyclopedic phrasing table might be better moved to a more general article. This article may require cleanup to meet Wikipedia's quality standards.
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